About Us

In our laboratory we are interested in understanding the neural processing involved to achieve vision. We focus on the first steps of vision: retinal and post retinal pathways. Particular attention is given to color and brightness perception and how early processing affects it (for example, the mechanisms of light adaptation). Also, we study pupillometry as a biomarker of retinal functioning to early detect diseases affecting the retina.
We approach these subjects with experimental techniques such as psychophysics, pupillometry, and electroretinography, and using computational methods, such as natural image statistics.
Our lab belongs to the Basic and Applied Vision Group of the Institute of Research in Light, Environment, and Vision (ILAV, by its acronym in Spanish), double dependency institute (National University of Tucumán, UNT, and National Council for Scientific and Technical Research, CONICET), Argentina.


Pablo A. Barrionuevo

B.S.(E.E.), M.Sc., Ph.D

Associate Researcher
Institute of Research in Light, Environment, and Vision (ILAV), UNT - CONICET.
ORCID, Scopus, Scholar
Keywords: Vision, Photoreceptors, Melanopsin, Color, Brightness, Adaptation, Pupillometry.

María Leonor Sandoval

B.S.(BiolS), Ed.S., Ph.D.

Assistant Researcher
Institute of Research in Light, Environment, and Vision (ILAV), UNT - CONICET & Institute of Research in Argentine Biodiversity (PIDBA), UNT.
ORCID, Scopus, Scholar
Keywords: Biological Specimens, Color Deterioration, Color Patterns, Mammals, Pelage, Taxonomy, Vision.

Constanza Tripolone


Senior Ph. D. Candidate
Institute of Research in Light, Environment, and Vision (ILAV), UNT - CONICET.
Keywords: Chromatic Pupillometry, Glaucoma, Retina, Non-invasive Diagnosis Techniques

José Fanchini

B. A.

Junior Ph. D. Candidate
Institute of Research in Light, Environment, and Vision (ILAV), UNT - CONICET.
Keywords: Chromatic Adaptation, Color grading, Spectral Imaging


    • Luis Issolio: Independent Researcher ILAV
    • Iñaki Cormenzana Mendez: Software Developer
    • Bárbara Silva: Colorimetry Lab Manager
    • Mariano Campos: Technical assistant
    • Andrés Martín: Associate Researcher ILAV
    • Oscar Preciado: Assistant Researcher ILAV
    • Agustín Gutierrez: Undergraduate student


  1. Barrionuevo, P. A., Issolio, L. A., & Tripolone, C. (2023). Photoreceptor contributions to the human pupil light reflex. Journal of Photochemistry and Photobiology, 15, 100178.
  2. Martínez, JJ, Sánchez RT, Sandoval Salinas ML, García CG, Barquez RM, Ferro I. 2022. Species differentiation in two closely related Neotropical rodents across a transition zone between ecoregions. Mammalian Biology,
  3. Barrionuevo, P. A., Filgueira, C. P., & Cao, D. (2022). Is melanopsin activation affecting large field color-matching functions? JOSA A, 39(6), 1104–1110.
  4. Barrionuevo, P. A., Preciado Olvera, O. U., Sandoval Salinas, M. L., & Issolio, L. A. (2022). Optical stimulation systems for studying human vision. In N. Santhi, & M. Spitschan (Eds.), Progress in Brain Research (Vol. 273, pp. 13–32). Elsevier
  5. Cormenzana Méndez, I., Martín, A., O’Donell, B., Cao, D., & Barrionuevo, P. A. (2022). Temporal integration of rod signals in luminance and chromatic pathways. JOSA A, 39(10), 1782–1793.
  6. Tripolone, M. C., Issolio, L. A., Agüero, C., Lavaque, A., Cao, D., & Barrionuevo, P. A. (2022). Comparing flickering and pulsed chromatic pupil light responses. JOSA A, 39(8), 1505–1512.
  7. Sandoval Salinas ML, Díaz MM, Ferro I, Barquez RM. Patrones biogeográficos de los murciélagos de Argentina: riqueza de especies y congruencia distribucional. Mastozoologia Neotropical. 2021;28(1):NA-NA. doi:10.31687/saremMN.
  8. Vicente EG, Arranz I, Galarreta D, et al. Effect of Different Spectral Power Distributions on Mesopic Visual Performance with Blue Light-filtering Intraocular Lens. LEUKOS. 2021;17(1):59-74. doi:10.1080/15502724.2020.175746
  9. Sandoval Salinas ML, Sandoval JD, Colombo EM. Sobre la determinación subjetiva del color de especímenes biológicos: el caso del pelaje de pequeños mamíferos. In: ANALES AFA. ; 2018:11-19. doi:10.31527/analesafa.2018.inVisionT.11
  10. Sandoval Salinas ML, Sandoval JD, Colombo EM, Barquez RM. The pattern of color change in small mammal museum specimens: is it independent of storage histories given museum-specific conditions? BMC Res Notes. 2018;11(1):424. doi:10.1186/s13104-018-3544-x
  11. Karas FI, Arteaga A, Barrionuevo P, et al. Intraocular Light Scatter in Eyes With the Boston Type 1 Keratoprosthesis. Cornea. 2019;38(1):50-53. doi:10.1097/ICO.0000000000001724
  12. Barrionuevo PA, Cao D. Does melanopsin help to explain color constancy in natural environments? In: Proceedings of the International Color Association (AIC) Conference 2019. International Colour Association Incorporated; 2019:598-605.
  13. Tripolone MC, Issolio L, Silva B, Paz Filgueira C, Perez D, Barrionuevo P. Sensibilidad al contraste en pacientes con glaucoma temprano: efectos del nivel de iluminación y la excentricidad. ANALES AFA. 2018;Número Especial inVisionT:62-66. doi:10.31527/analesafa.2018.inVisionT.62
  14. Preciado Olvera OU, Luis I, Manzano E, Colombo E, Barrionuevo P. Melanopsin excitation in conditions of natural and artificial lighting. Anales AFA. 2018;29:25-30. doi:10.31527/analesafa.2018.inVisionT.25
  15. Feitosa-Santana C, Lutze M, Barrionuevo PA, Cao D. Assessment of #TheDress With Traditional Color Vision Tests: Perception Differences Are Associated With Blueness. i-Perception. 2018;9(2):2041669518764192. doi:10.1177/2041669518764192
  16. Barrionuevo PA, McAnany JJ, Zele AJ, Cao D. Non-linearities in the Rod and Cone Photoreceptor Inputs to the Afferent Pupil Light Response. Front Neurol. 2018;9. doi:10.3389/fneur.2018.01140
  17. Barrionuevo PA, Matesanz BM, Gloriani AH, et al. Effect of eccentricity and light level on the timing of light adaptation mechanisms. J Opt Soc Am A, JOSAA. 2018;35(4):B144-B151. doi:10.1364/JOSAA.35.00B144
  18. Sandoval Salinas ML, Barquez RM, Colombo EM, Sandoval JD. Intra-specific pelage color variation in a South American small rodent species. Brazilian Journal of Biology. 2017;77(1):1-11. doi:10.1590/1519-6984.00615
  19. Sandoval Salinas ML, Sandoval JD, Colombo EM. Objective measurement of Akodon budini dorsal coloration: methodological concerns. Anais da Academia Brasileira de Ciências. 2016;88:489-502. doi:10.1590/0001-3765201620150004
  20. Martínez JJ, Sandoval Salinas ML, Carrizo LV. Taxonomic status of large-and middle-sized Calomys (Cricetidae: Sigmodontinae) from the southern central Andes inferred through geometric morphometrics of the skull. Journal of Mammalogy. 2016;97(6):1589-1601. doi:10.1093/jmammal/gyw123
  21. Santillán JE, Martín A, Barrionuevo PA, Nano ME, Lansingh V. Vidrios oscurecidos en automotores: normalización e información oftalmológica. Oftalmología Clínica y Experimental. 2016;9(4):170-177.
  22. Gloriani AH, Matesanz BM, Barrionuevo PA, et al. Influence of background size, luminance and eccentricity on different adaptation mechanisms. Vision Research. 2016;125:12-22. doi:10.1016/j.visres.2016.04.008
  23. Barrionuevo PA, Cao D. Luminance and chromatic signals interact differently with melanopsin activation to control the pupil light response. Journal of Vision. 2016;16(11):29. doi:10.1167/16.11.29

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